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Canine mastocytoma: report of 8 cases diagnosed by fine needle cytology andclinicopathologic correlations

April 12, 2008 By: admin Category: Environmental Science and Ecology, Life Sciences

BACKGROUND: Mast cell proliferations are commoner in dogs than in humans;mass forming lesions in the former are apt to fine needle sampling and the obtained cytopathologicalpicture might be informing to enhance recognition of similar proliferations in humans. CASE:Clinical and cytopathologic data were collected from 8 cases of canine mastocytomas diagnosed byfine needle cytology. The cytopathologic presentation was correlated with the individual therapyperformed and with the clinical stage. In all cases the cytopathological diagnosis was confirmed byhistopathologic examination of the excised mass, by necropsy or by response to therapy. CONCLUSION:There are marked similarities between canine and human mastocytomas, despite possible differences inthe clinical course of the disease in both species. Canine mastocytomas may hence be used as ananimal model of a human disease and, as such, familiarity with their cytologic presentation may beuseful for recognizing mast cell proliferations in humans

Fulciniti,F Di-Mattia,D Curcio,MP Bove,P Rota,AM Botti,G
Section of Cytodiagnosis, National Tumor Institute “Fondazione G. Pascale,”Naples, Italy. franco.fulciniti@gmail.com

Mastocytoma, NOS  Legal fine Clinical Cellular