Testicular juvenile granulosa cell tumor:a case report
BACKGROUND: Juvenile granulosa cell tumors of the testis are rare gonadalstromal tumors of the pediatric age. They represent the most common neoplasms of the testis in thefirst 6 months of life. A testicular cystic mass is detected, or it can appear as an abdominal oringuinal mass. Differential diagnosis for testicular tumors at this age includes teratoma, simplecyst, epidermoid cyst, lymphangioma and testicular torsion. Association with ambiguous genitalia andsex chromosome abnormalities has been reported. Orchiectomy alone is recommended, because no caseof metastasis or recurrence has been reported. CASE: We report a case of a 3-month-old male infantwith a testicular juvenile granulosa cell tumor mass initially evaluated by fine needle biopsy,which disclosed single or cohesive groups of vimentin, alpha-inhibin and S-100-positive spindlecells with regular nuclei and fine chromatin and inconspicuous nucleoli. Orchiectomy was performed,and histology revealed a juvenile granulosa cell tumor. CONCLUSION: Even though juvenile granulosacell tumor is the most common neoplasm of the testis in the first 6 months of life, we found noreports describing its cytologic features. In this setting, fine needle aspiration cytology is auseful tool for initial and therapeutic management.
Barroca,H　Gil-da-Costa,MJ　Mariz,C
Anatomy and Pathology Service, Sao Joao Hospital, Porto, Portugal.hbarroca@gmail.com
Neoplasms　 Juvenile　 Granulosa Cells　 month Testis
