China Science

BACKGROUND: Although the histologic features of malignant peripheral nervesheath tumor (MPNST) have been described, the cytologic features of primary pulmonary MPNST have notbeen reported in the literature. CASE: We report a case of primary pulmonary MPNST in a 78-year-oldman. Follow-up computed tomography of colon cancer, renal cancer, penile cancer and gingival cancerrevealed a nodular lesion, 12 mm in diameter, in the right upper lobe of the lung. (more…)

BACKGROUND: Mastocytosis is an abnormal proliferation of mast cells and theirsubsequent accumulation in various organs. Diagnosis of mast cell disease relies on properidentification of abnormal mast cells. CASE: A 55-year-old man presented with a history of fever forseveral months, associated with night sweats, involuntary 20lb weight loss, (more…)

BACKGROUND: To describe the cytologic, histologic and immunohistochemicalfindings of a case of epithelial myoepithelial carcinoma (EMC) arising from a pleomorphic adenoma(PA) of the parotid with both malignant epithelial and myoepithelial components. CASE: A 29-year-oldfemale presented with a 1.5 x 1.5-cm, palpable mass of the left parotid of 7-8 months’ durationwith recent enlargement and pain. Fine needle aspiration biopsy (FNAB) revealed biphasic epithelial(small cell) and myoepithelial (large/clear cell) clusters arranged in a pseudopapillary andtrabecular pattern with abundant hyaline material with many naked nuclei, together with areastypical of pleomorphic adenoma (PA) was noted. (more…)

BACKGROUND: Filariasis is a major public health problem in developingcountries, and the diagnosis is conventionally made by demonstrating microfilariae in the peripheralblood smear. However, microfilariae have been incidentally detected in fine needle aspirates ofvarious lesions in clinically unsuspected cases of filariasis with absence of microfilariae in theperipheral blood. CASES: In case 1, a 21-year-old woman presented with multiple left axillarylymphadenopathy of 3 months’ duration. In case 2, a 32-year-old woman presented with a thyroidnodule of 7 months’ duration. (more…)

BACKGROUND: Erythema nodosum leprosum (ENL), the type 2 lepra reactionoccurring in lepromatous or borderline lepromatous leprosy, presents clinically with acutemanifestations that compel the patient to seek medical attention. Recognition and timely managementof these patients is critical in order to avoid permanent disability. Fine needle aspirationcytology (FNAC) is a simple, effective tool that aids in correct diagnosis and management of ENL.CASE: (more…)

OBJECTIVE: To evaluate the usefulness of toluidine blue and brush biopsy inprecancerous oral lesions and squamous cell carcinoma. STUDY DESIGN: The study was conducted at MotiLal Nehru Medical College, Allahabad, India. (more…)

OBJECTIVE: To evaluate the smear quality and diagnostic accuracy of ThinPrepprocessing in comparison to conventional Cytospin technique for urinary cytology. STUDY DESIGN:ThinPrep and Cytospin techniques were retrospectively evaluated by 2 observers in a double-blinded,randomized fashion. (more…)

OBJECTIVE: To reveal the diagnostic and prognostic significance ofeosinophilic pleural effusions (EPEs) and assess their clinical implications. STUDY DESIGN: SeventyEPEs from 60 patients among 697 consecutive pleural effusions were investigated from 1996-2005 atKocaeli University Hospital, Kocaeli, Turkey. (more…)