Mason,SG; Bashashati,A; Fatourechi,M; Navarro,KF; Birch,GE
Abstract In this work we present the first comprehensive survey of Brain Interface(BI) technology designs published prior to January 2006. Detailed results from this survey, whichwas based on the Brain Interface Design Framework proposed by Mason and Birch, are presented anddiscussed to address the following research questions: (more…)
Taylor,AB; Borhan,A; Ultman,JS
Abstract The pattern of lung injury induced by the inhalation of ozone (O(3)) dependson the dose delivered to different tissues in the airways. This study examined the distribution ofO(3) uptake in a single, symmetrically branched airway bifurcation. Reaction in the epitheliallining fluid was assumed to be so rapid that O(3) concentration was negligible along the entiresurface of the bifurcation wall. (more…)
Gawlitta,D; Li,W; Oomens,CW; Baaijens,FP; Bader,DL; Bouten,CV
Abstract Deep pressure ulcers develop in tissues subjected to sustained mechanicalloading. Though it has been hypothesized that this damage mechanism results from local tissueischemia, it has recently been shown with a cell model that sustained compression can cause celldeformation, leading to tissue breakdown. (more…)
Bischof,JC; Mahr,B; Choi,JH; Behling,M; Mewes,D
Abstract The outcome of both cryopreservation and cryosurgical freezing applicationsis influenced by the concentration and type of the cryoprotective agent (CPA) or the cryodestructiveagent (i.e., the chemical adjuvants referred to here as CDA) added prior to freezing. It alsodepends on the amount and type of crystalline, amorphous and/or eutectic phases formed duringfreezing which can differentially affect viability. (more…)
Baumert,M; Wessel,N; Schirdewan,A; Voss,A; Abbott,D
Abstract Ventricular tachycardia (VT) provokes sudden cardiac death (SCD), which is amajor cause of mortality in developed countries. Implantable cardioverter-defibrillators (ICDs) arean efficient therapy for SCD prevention. In this study we analyze heart rate variability (HRV) indata stored by ICDs. In 29 patients exhibiting VT episodes, (more…)
Ferko,MC; Bhatnagar,A; Garcia,MB; Butler,PJ
Abstract Hemodynamic forces applied at the apical surface of vascular endothelialcells may be redistributed to and amplified at remote intracellular organelles and protein complexeswhere they are transduced to biochemical signals. In this study we sought to quantify the effectsof cellular material inhomogeneities and discrete attachment points on intracellular stressesresulting from physiological fluid flow. (more…)
Cheng,T; Dai,C; Gan,RZ
Abstract The tympanic membrane or eardrum of human ear transfers sound waves intomechanical vibration from the external ear canal into the middle ear and cochlea. Mechanicalproperties of the tympanic membrane (TM) play an important role in sound transmission through theear. (more…)
Stemper,BD; Yoganandan,N; Sinson,GP; Gennarelli,TA; Stineman,MR; Pintar,FA
Abstract Blunt carotid artery injuries occur in 0.3% of blunt injured patients and maylead to devastating neurological consequences. However, arterial mechanics leading to internallayer subfailure have not been quantified. Twenty-two human carotid artery segments and 18 porcinethoracic aorta segments were opened to expose the intimal side and longitudinally distracted tofailure. (more…)
