Fluid bed drying of guarana ( Paullinia cupana HBK) extract: Effect of process factors on caffeine content

The aim of this study was to study the convective drying of the hydroalcoholic extracts obtained from powdered guarana seeds in a spouted bed dryer. The influence of process variables, such as the convective airflow rate, extract feed rate,; air… Read moreFluid bed drying of guarana ( Paullinia cupana HBK) extract: Effect of process factors on caffeine content

Dissolution improvement of high drug-loaded solid dispersion

This study focused on an investigation of a high drug-loaded solid dispersion system consisting of drug, carrier,; surfactant. Solid dispersions of a water-insoluble ofloxacin (OFX) with polyethylene glycol (PEG) of different molecular weights, namely binary solid dispersion systems, were prepared… Read moreDissolution improvement of high drug-loaded solid dispersion

Studies on effect of pH on cross-linking of chitosan with sodium tripolyphosphate: A technical note

Conclusions The ionotropic gelation method for formation of crosslinked chitosan particles can be easily modified from ionic cross-linking to deprotonation by adjusting the pH of TPP. Chitosan was cross-linked ionically with TPP at lower pH; by deprotonation mechanism at higher… Read moreStudies on effect of pH on cross-linking of chitosan with sodium tripolyphosphate: A technical note

Commerical reference shape standards use in the study of particle shape effect on laser diffraction particle size analysis

The purpose of this paper is to describe the use of LGC Promochem AEA 1001 to AEA 1003 monosized fiberanalog shape standards in the study of the effect of particle shape on laser diffraction (LD) particle size analysis (psa). The… Read moreCommerical reference shape standards use in the study of particle shape effect on laser diffraction particle size analysis

Spherical agglomeration of mefenamic acid; nabumetone to improve micromeritics; solubility: A technical note

Conclusions Spherical agglomeration techniques were developed for improving the flow; compressibility characteristics of microcrystalline mefenamic acid; nabumetone. The process involved agglomerating microcrystals using agglomerating solvents. Temperature; speed of agitation were optimized to obtain spherical agglomerates in a desired range, which… Read moreSpherical agglomeration of mefenamic acid; nabumetone to improve micromeritics; solubility: A technical note

Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater: Part 2: Application of the model

For the prediction of the air; product temperatures, the product moisture,; the air humidity during a coating process in a Bohle Lab-Coater, a model was developed. The purpose of this work was to determine the limit moisture, the critical moisture,;… Read moreMathematical modeling of an aqueous film coating process in a Bohle Lab-Coater: Part 2: Application of the model

Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater, Part 1: Development of the model

The purpose of this study was to develop a model to predict (1) air; product temperatures, (2) product moisture,; (3) air humidity during an aqueous coating process using a Bohle Lab-Coater. Because of the geometrical properties; the airflow, the drum… Read moreMathematical modeling of an aqueous film coating process in a Bohle Lab-Coater, Part 1: Development of the model