Science Publications

BACKGROUND: Absolute criteria for grading oligodendrogliomas are somewhatpoorly defined in contrast to those for grading astrocytic tumors, and cytologic features ofanaplastic oligodendrogliomas have been poorly described. CASE: A 63-year-old man presented with atoppling gait. Radiologic examination revealed a 7-cm mass with calcifications in the right frontallobe. Intraoperative smears of the tumor showed hypercellular, loosely cohesive cell clusters andsingle cells with nuclear pleomorphism, numerous apoptotic cells and no discernible fibrillaryprocesses. (more…)

BACKGROUND: Cerebrotendinous xanthomatosis is a rare, autosomal recessive,inherited lipid storage disease characterized by accumulation of cholestanol and cholesterol in mosttissues. The disease is caused by mutations in the sterol 27-hydroxylase gene, leading to a blockin bile synthesis, with accumulation of substrates for this enzyme, including cholesterol, resultingin an increase in the conversion of cholesterol to cholestanol. (more…)

BACKGROUND: Cystic nephroma is an uncommon pediatric renal neoplasm. It needsto be differentiated from cystic partially differentiated nephroblastoma and from other renalneoplasms showing extensive cystic change. (more…)

BACKGROUND: Sporotrichosis is a granulomatous fungal infection caused bySporothrix schenckii, which frequently causes cutaneous or lymphocutaneous lesions and rarely hasoral manifestations. (more…)

BACKGROUND: Since the first description of extranodalfollicular dendriticcell sarcoma in 1994, there has been a gradual increase in understanding of the morphologic featuresand clinical presentation of this tumor. (more…)

BACKGROUND: Carcinoma metastatic to the pituitary gland is infrequent and hasbeen reportedly detected in approximately 1% of pituitary surgical cases. It may masquerade as apituitary adenoma both clinically and radiologically. (more…)

BACKGROUND: Juvenile granulosa cell tumors of the testis are rare gonadalstromal tumors of the pediatric age. They represent the most common neoplasms of the testis in thefirst 6 months of life. A testicular cystic mass is detected, or it can appear as an abdominal oringuinal mass. Differential diagnosis for testicular tumors at this age includes teratoma, simplecyst, epidermoid cyst, lymphangioma and testicular torsion. (more…)

BACKGROUND: The occurrence of a primary intramuscular infestation ofEchinococcus granulosus is extremely rare. CASE: A 70-year-old woman with primary skeletal musclehydatidosis initially presented with a soft tissue mass. (more…)