McDonnell,P; McHugh,PE; O”Mahoney,D
Abstract Vertebral fractures due to osteoporosis commonly occur under non-traumaticloading conditions. This problem affects more than 1 in 3 women and 1 in 10 men over a lifetime.Measurement of bone mineral density (BMD) has traditionally been used as a method for diagnosis ofvertebral osteoporosis. However, this method does not fully account for the influence of changes inthe trabecular bone quality, such as micro-architecture, tissue properties and levels ofmicrodamage, on the strength of the vertebra. Studies have shown that deterioration of the vertebraltrabecular architecture results in a more anisotropic structure which has a greater susceptibilityto fracture. (more…)